About PeptideSciences101
Mission
PeptideSciences101 exists to make peptide science legible. We consolidate mechanism of action, clinical evidence, dosing protocols, combination strategies, and safety data from primary literature into one encyclopedic reference — the kind of resource we wanted to find when we started reading the field and couldn’t.
We are pro-peptide and pro-transparency. In practice that means we document what the evidence actually says — including when the evidence is weak, anecdotal, or contradictory — rather than picking a marketing position. We separate FDA-approved therapeutics from research compounds and note the regulatory status by jurisdiction. We cite primary sources and link to them where they exist. We do not sell peptides; the vendor directory is informational only and we take no commission from any vendor listed.
Why this site exists
Peptide information online is fractured. Reliable material is buried on PubMed behind technical language; accessible material lives on forums and vendor sites with no editorial standard at all. Useful summaries get lost to broken links, deleted Reddit threads, and paywalls. We started PeptideSciences101 to bring those threads together in one place — written plainly, sourced honestly, and maintained over time the way Wikipedia is maintained.
We are not anti-pharmaceutical and we are not a wellness brand. We are a reference. If an article reads like an advertisement or like a warning label, we’ve gotten it wrong and we want to hear about it.
Editorial team
PeptideSciences101 is founder-led, with the goal of becoming community-edited the way Wikipedia is.
- James Bryan — founder and editor-in-chief. Responsible for the editorial framework, article structure, and the corrections process. James is not a licensed clinician; articles concerning clinical use are reviewed against published primary sources, not personal clinical judgment.
- Outside reviewers — peer reviewers with backgrounds in biochemistry, clinical pharmacology, and medicine are credited at the bottom of articles they touch. Reviewer credentials are listed publicly; reviewers do not receive payment tied to article framing.
If you are a clinician, researcher, or pharmacist and want to review articles in your area of expertise, email the editorial address below.
Editorial process
Every article moves through four stages:
- Draft. An initial summary is written from primary literature with citations attached. Drafts are not published.
- Source verification. Each non-trivial claim is traced back to a peer-reviewed paper, an FDA document, or a published trial registry entry. Claims that cannot be sourced are removed or flagged.
- Peer review. A reviewer with subject-matter background reads the draft and marks anything that overstates or understates the evidence.
- Publish. The article goes live with an evidence tag (see below), a visible last-updated date, and a complete References section.
Evidence tags
Every article and every protocol carries an evidence label so you can see at a glance how strong the underlying support is:
- Regulatory label — drawn from FDA-approved labelling or an equivalent national regulator. The strongest tier.
- Systematic review / randomized trial — drawn from high-quality peer-reviewed clinical research.
- Observational / case series — drawn from smaller human studies, retrospective analyses, or case reports.
- Expert opinion / anecdotal — drawn from community reports, practitioner consensus, or unpublished experience. Useful, but the weakest tier — treated as such.
What we cover (and don’t)
In scope: bioactive peptides used or studied in humans for performance, recovery, longevity, metabolic disease, cosmetic, and clinical indications; FDA-approved peptide therapeutics; common combinations and stacks; published safety data; jurisdictional regulatory status.
Out of scope: direct medical recommendations; procurement instructions; sourcing or substitution of prescription drugs; anything that is illegal to perform in the reader’s jurisdiction. We will describe what compounds doand what the literature reports about them. We will not tell you what to take, how to acquire it, or that it’s safe for you.
Corrections & updates
If you find an error, email info@jabsystems.io with the article URL and the specific claim you’re flagging. Include a citation if you have one. We try to respond within 72 hours and to publish corrections within seven days of confirming them.
Substantive corrections (not typos) are noted at the bottom of the affected article with the date of the change and a one-line description of what was corrected. We do not silently rewrite articles.
How we’re funded
PeptideSciences101 is reader-supported. Hosting, database costs, editorial review, and primary-source access are paid for by subscriptions through three tiers — Supporter, Patron, and Benefactor — explained in detail on the Support us page. The basic peptide catalog, the FDA-approved drug index, the vendor directory, and forum reading are free for everyone. Deep-dive articles and forum posting are reserved for paid members.
We do not take vendor payments. The vendor directory is maintained as a reference and inclusion is not for sale. We do not run banner advertising, affiliate links, or sponsored content.
How to contribute
There are four ways to contribute, in increasing order of involvement:
- Flag a problem. Email info@jabsystems.io with the article URL and what’s wrong.
- Suggest a citation. If an article is missing a primary source you know about, send the DOI or PubMed ID and where in the article it belongs.
- Request an article. Post in the forum with the compound and why you think it warrants coverage.
- Peer-review articles. If you have a relevant background, email the editorial address with a short note about your training and which areas you’d like to review.
Disclaimer
Nothing on PeptideSciences101 constitutes medical advice. Articles are educational. Many peptides discussed here are not approved for human use and may be illegal to possess or administer in your jurisdiction; some are prescription-only drugs. Always consult a licensed clinician before using any compound discussed on this site.
PeptideSciences101 makes no warranty about the accuracy, completeness, or currency of any information presented. Dosing ranges, protocols, and side-effect profiles are summaries of published literature and reported experience, not prescriptions. The complete legal terms are in the Terms of Use.
Contact
For corrections, contributions, peer review, and press, email info@jabsystems.io. For account or billing questions, use the same address and include the email on your account.
PeptideSciences101 is operated by JAB Systems. Mailing address and registered agent details will be added once entity registration is complete.