Imunofan vs LL-37

A side-by-side comparison from PeptideSciences101, the open peptide reference.

Overview

Imunofan is primarily a immune support peptide, while LL-37 is used for pain management.

This page compares Imunofan and LL-37 across their primary use, typical dosing, reported benefits and side effects, and U.S. regulatory status. For the full monograph on either compound — mechanism of action, clinical research, and references — follow the article links.

Side-by-side comparison

ImunofanLL-37
CategoryImmune SupportPain Management
Regulatory status (US)Research use onlyCompounding (Rx) — Apr 2026
Typical dosage1 mg2-5 mg
Frequencydaily for 10 daystwice weekly
Reported benefitsImmune enhancement, detoxification support, antioxidant effectsInflammation-related pain relief, infection-related pain support
Reported side effectsWell-toleratedGenerally safe

Key differences

Primary use. Imunofan is categorised under Immune Support, while LL-37 falls under Pain Management. Their differing categories mean they are usually chosen for different goals rather than as direct substitutes.

Regulatory status. Imunofan: not FDA-approved; treated as a research compound. LL-37: not FDA-approved; compounding permitted with a prescription as of April 2026.

Dosing. Imunofan is typically dosed at 1 mg (daily for 10 days). LL-37 is typically dosed at 2-5 mg (twice weekly).

Can you stack them?

Some protocols combine peptides, but stacking Imunofan and LL-37 has not been validated for safety or efficacy in controlled trials. Combining compounds can change their effects and risks. Nothing here is medical advice — consult a qualified healthcare provider before starting or combining any protocol.

Frequently asked questions

What is the difference between Imunofan and LL-37?
Imunofan is primarily a immune support peptide, while LL-37 is used for pain management. Imunofan is not FDA-approved; generally classified as a research compound, whereas LL-37 is not FDA-approved; compounding permitted with a prescription (as of April 2026).
What is Imunofan used for?
Russian immune peptide.
What is LL-37 used for?
Inflammatory pain modulation.
Can you take Imunofan and LL-37 together?
Some users combine peptides within a single protocol, but stacking Imunofan and LL-37 has not been established as safe or effective in controlled trials. Neither this comparison nor PeptideSciences101 is medical advice — consult a qualified healthcare provider before combining any compounds.
Is Imunofan or LL-37 FDA-approved?
Imunofan is not FDA-approved; generally classified as a research compound. LL-37 is not FDA-approved; compounding permitted with a prescription (as of April 2026).

Read the full articles

  • Imunofan — full monograph: mechanism, research, dosing & references
  • LL-37 — full monograph: mechanism, research, dosing & references

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