Lanreotide vs TB-500

A side-by-side comparison from PeptideSciences101, the open peptide reference.

Overview

Lanreotide is primarily a hormonal peptide, while TB-500 is used for healing & recovery.

This page compares Lanreotide and TB-500 across their primary use, typical dosing, reported benefits and side effects, and U.S. regulatory status. For the full monograph on either compound — mechanism of action, clinical research, and references — follow the article links.

Side-by-side comparison

LanreotideTB-500
CategoryHormonalHealing & Recovery
Regulatory status (US)FDA approvedCompounding (Rx) — Apr 2026
Typical dosage60-120 mg2-5 mg
Frequencyevery 4 weeksweekly
Reported benefitssuppression of excess growth hormone and IGF-1 in acromegaly, improved progression-free survival in GEP-NETs, reduction of carcinoid syndrome symptoms, inhibition of multiple GI and pancreatic hormonesTissue repair, improved flexibility, reduced inflammation, enhanced recovery, hair growth stimulation
Reported side effectsdiarrhea, cholelithiasis, abdominal pain, hyperglycemia, bradycardia, injection site reactions, nausea, hypertension, headache, thyroid function decreasesMinimal side effects. Rare: headache, nausea, injection site reactions

Key differences

Primary use. Lanreotide is categorised under Hormonal, while TB-500 falls under Healing & Recovery. Their differing categories mean they are usually chosen for different goals rather than as direct substitutes.

Regulatory status. Lanreotide: FDA-approved. TB-500: not FDA-approved; compounding permitted with a prescription as of April 2026.

Dosing. Lanreotide is typically dosed at 60-120 mg (every 4 weeks). TB-500 is typically dosed at 2-5 mg (weekly).

Can you stack them?

Some protocols combine peptides, but stacking Lanreotide and TB-500 has not been validated for safety or efficacy in controlled trials. Combining compounds can change their effects and risks. Nothing here is medical advice — consult a qualified healthcare provider before starting or combining any protocol.

Frequently asked questions

What is the difference between Lanreotide and TB-500?
Lanreotide is primarily a hormonal peptide, while TB-500 is used for healing & recovery. Lanreotide is FDA-approved for one or more indications, whereas TB-500 is not FDA-approved; compounding permitted with a prescription (as of April 2026).
What is Lanreotide used for?
FDA-approved long-acting somatostatin analog for acromegaly, GEP-NETs, and carcinoid syndrome.
What is TB-500 used for?
Tissue repair, flexibility, inflammation.
Can you take Lanreotide and TB-500 together?
Some users combine peptides within a single protocol, but stacking Lanreotide and TB-500 has not been established as safe or effective in controlled trials. Neither this comparison nor PeptideSciences101 is medical advice — consult a qualified healthcare provider before combining any compounds.
Is Lanreotide or TB-500 FDA-approved?
Lanreotide is FDA-approved for one or more indications. TB-500 is not FDA-approved; compounding permitted with a prescription (as of April 2026).

Read the full articles

  • Lanreotide — full monograph: mechanism, research, dosing & references
  • TB-500 — full monograph: mechanism, research, dosing & references

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